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  1. Lipids are an important source for energy production during oocyte maturation. The accumulation of intracellular lipids binds to proteins to form lipid droplets. This may lead to cellular lipotoxicity. The imp...

    Authors: Shira Raviv, Shay Hantisteanu, Shilhav Meisel Sharon, Yuval Atzmon, Mediea Michaeli and Einat Shalom-Paz

    Citation: Journal of Ovarian Research 2020 13:4

    Content type: Research

    Published on:

  2. Acute myeloid leukemia (AML) in monozygotic twins is a rare event and, until now, only a few cases have been reported. Due to improved oncological treatment and cancer survival rates, quality of life considera...

    Authors: Tanja Burnik Papler, Eda Vrtacnik Bokal and Nina Jančar

    Citation: Journal of Ovarian Research 2020 13:2

    Content type: Case report

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  3. Secondary cytoreductive surgery (SCS) is possible in selected patients with recurrent epithelial ovarian cancer (EOC). The goal of SCS is complete resection, although chemotherapy is always followed. Delayed i...

    Authors: Soo Young Jeong, Chel Hun Choi, Tae Joong Kim, Jeong Won Lee, Byoung-Gie Kim, Duk Soo Bae and Yoo-Young Lee

    Citation: Journal of Ovarian Research 2019 13:1

    Content type: Research

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  5. Ovarian cancer is the most lethal gynaecologic malignancy. Although there are various subtypes of ovarian cancer, high-grade serous ovarian cancer (HGSOC) accounts for 70% of ovarian cancer deaths. Chemoresist...

    Authors: Huan Wu, Rongrong Li, Zhiwei Zhang, Huiyang Jiang, Hanlin Ma, Cunzhong Yuan, Chenggong Sun, Yingwei Li and Beihua Kong

    Citation: Journal of Ovarian Research 2019 12:125

    Content type: Research

    Published on:

    The Correction to this article has been published in Journal of Ovarian Research 2020 13:28

  6. Alpha-fetoprotein (AFP) plays a crucial role in the management of malignant ovarian germ cell tumors (MOGCTs) and is an important reference index for chemotherapy termination. However, a high level of AFP can ...

    Authors: Xuan Zong, Jia-Xin Yang and Ying Zhang

    Citation: Journal of Ovarian Research 2019 12:124

    Content type: Case report

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  7. Endometriosis is considered to be the most intractable cause of female infertility. Administering any type of treatment for endometriosis before in vitro fertilization and embryo transfer (IVF-ET) is an import...

    Authors: Hiroshi Tamura, Hiroaki Yoshida, Hiroyuki Kikuchi, Mai Josaki, Yumiko Mihara, Yuichro Shirafuta, Masahiro Shinagawa, Isao Tamura, Toshiaki Taketani, Akihisa Takasaki and Norihiro Sugino

    Citation: Journal of Ovarian Research 2019 12:123

    Content type: Research

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  8. Epithelial ovarian cancer (EOC) is the deadliest female malignancy. The Wnt/β-catenin pathway plays critical roles in regulating embryonic development and physiological processes. This pathway is tightly regul...

    Authors: Vu Hong Loan Nguyen, Rebecca Hough, Stefanie Bernaudo and Chun Peng

    Citation: Journal of Ovarian Research 2019 12:122

    Content type: Review

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  9. Increasing researches have demonstrated the critical functions of MicroRNAs (miRNAs) in the progression of malignant tumors, including ovarian cancer. It was reported that miR-552 was an important oncogene in ...

    Authors: Wenman Zhao, Tao Han, Bao Li, Qianyun Ma, Pinghua Yang and Hengyu Li

    Citation: Journal of Ovarian Research 2019 12:121

    Content type: Research

    Published on:

  10. Ovarian cancer has the highest ratio of mortality among gynecologic malignancies. Chemotherapy is one of the most common treatment options for ovarian cancer. However, tumor relapse in patients with advanced t...

    Authors: Vahideh Keyvani, Moein Farshchian, Seyed-Alireza Esmaeili, Hadi Yari, Meysam Moghbeli, Seyed-Reza Kazemi Nezhad and Mohammad Reza Abbaszadegan

    Citation: Journal of Ovarian Research 2019 12:120

    Content type: Review

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  12. Ovarian cancer (OC) is a type of gynaecological malignancy with high mortality in females. Serous ovarian cancer (SOC) is a distinct subtype of OC with poor early diagnosis. Given the limitations of traditiona...

    Authors: Zhi-Ying Qi, Fang Wang, Ying-Ying Yue, Xue-Wang Guo, Rui-Meng Guo, Hong-Lin Li and Yan-Ying Xu

    Citation: Journal of Ovarian Research 2019 12:118

    Content type: Research

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  13. Poly (ADP-ribose) polymerase (PARP) inhibitor, is a milestone in treatment of ovarian cancer. However, there is no real world study from China regarding the clinical outcome of the taking PARP inhibitor (PARPi...

    Authors: Jing Ni, Xianzhong Cheng, Rui Zhou, Xia Xu, Wenwen Guo and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2019 12:117

    Content type: Research

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  14. Cancer Antigen 125 (CA125) is currently the best available ovarian cancer screening biomarker. However, CA125 has been limited by low sensitivity and specificity in part due to normal variation between individ...

    Authors: Naoko Sasamoto, Ana Babic, Bernard A. Rosner, Renée T. Fortner, Allison F. Vitonis, Hidemi Yamamoto, Raina N. Fichorova, Linda J. Titus, Anne Tjønneland, Louise Hansen, Marina Kvaskoff, Agnès Fournier, Francesca Romana Mancini, Heiner Boeing, Antonia Trichopoulou, Eleni Peppa…

    Citation: Journal of Ovarian Research 2019 12:116

    Content type: Research

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  16. Growing evidence indicates that the tumor biomarker cytokeratin 19 fragment (CYFRA21-1) is significant for a variety of cancers. However, its role in epithelial ovarian cancer (EOC) has rarely been reported. I...

    Authors: Chunjing Jin, Minfeng Yang, Xueqiao Han, Haidan Chu, Yan Zhang, Meihong Lu, Zhonghui Wang, Xinxin Xu, Wenwen Liu, Feng Wang and Shaoqing Ju

    Citation: Journal of Ovarian Research 2019 12:114

    Content type: Research

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  17. Ovarian cancer is the leading cause of gynecological cancer-related mortality. The novel oncogene S100A10 has been reported to be involved in cancer cell proliferation, invasion and metastasis. The role of S10...

    Authors: Lingzhi Wang, Wei Yan, Xukun Li, Zhihua Liu, Tian Tian, Tanxiu Chen, Liang Zou and Zhumei Cui

    Citation: Journal of Ovarian Research 2019 12:113

    Content type: Research

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  18. Ovarian cancer is the leading cause of gynecologic cancer death in the United States despite effective first-line systemic chemotherapy. Cancer stem cells (CSCs) retain the ability to self-renew and proliferat...

    Authors: Elizabeth V. Connor, Caner Saygin, Chad Braley, Andrew C. Wiechert, Sheelarani Karunanithi, Katie Crean-Tate, Fadi W. Abdul-Karim, Chad M. Michener, Peter G. Rose, Justin D. Lathia and Ofer Reizes

    Citation: Journal of Ovarian Research 2019 12:112

    Content type: Research

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  19. Polycystic ovary syndrome (PCOS) is one of the most common endocrine diseases. At present, the cause of the disease is not fully understood, but many studies have shown that PCOS is associated with genetic and...

    Authors: Faezeh Tadaion Far, Shahideh Jahanian Sadatmahalleh, Saeideh Ziaei and Anoshirvan Kazemnejad

    Citation: Journal of Ovarian Research 2019 12:111

    Content type: Research

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  20. Ovarian cancer (OC) is the deadliest cause in the gynecological malignancies. Most OC patients are diagnosed in advanced stages with less than 40% of women cured. However, the possible mechanism underlying tum...

    Authors: Jiayu Shen, Shuqian Yu, Xiwen Sun, Meichen Yin, Jing Fei and Jianwei Zhou

    Citation: Journal of Ovarian Research 2019 12:110

    Content type: Research

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  21. Polycystic ovary syndrome (PCOS) is a complex endocrine disorder and regarded as the leading cause of anovulatory infertility. PCOS is characterized by reproductive dysfunction and metabolic disorders. Baicali...

    Authors: Wei Wang, Jiahua Zheng, Na Cui, Lei Jiang, Han Zhou, Dan Zhang and Guimin Hao

    Citation: Journal of Ovarian Research 2019 12:109

    Content type: Research

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  22. Ovarian cancer during pregnancy is relatively rare and treatment strategies are inexperienced in surgery and chemotherapy. Multidisciplinary management of advanced epithelial ovarian cancer in pregnant patient...

    Authors: Tianmin Xu, Liang Wang, Yan Jia, Zanhui Jia, Zhuo Li, Shaohai Cui and Manhua Cui

    Citation: Journal of Ovarian Research 2019 12:108

    Content type: Case report

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  23. Cisplatin-based chemotherapy is the first-line treatment for ovarian cancer. However, acquired resistance to cisplatin treatment often occurs in epithelial ovarian cancer, and effective and practical methods f...

    Authors: Bo Zhou, Meng Xia, Bin Wang, Niresh Thapa, Lijuan Gan, Chaoyang Sun, Ensong Guo, Jia Huang, Yulan Lu and Hongbin Cai

    Citation: Journal of Ovarian Research 2019 12:107

    Content type: Research

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  24. Ovarian carcinoma (OC) is a common cause of death among women with gynecological cancer. MicroRNAs (miRNAs) are believed to have vital roles in tumorigenesis of OC. Although miRNAs are broadly recognized in OC...

    Authors: Yaowei Li and Li Li

    Citation: Journal of Ovarian Research 2019 12:106

    Content type: Research

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  25. Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer in developed countries, indicating the need for further research. Although current cancer models prove useful, they have major limit...

    Authors: Sander Dumont, Ziga Jan, Ruben Heremans, Toon Van Gorp, Ignace Vergote and Dirk Timmerman

    Citation: Journal of Ovarian Research 2019 12:105

    Content type: Review

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  26. Young girls before menarche or menstruating adolescent women may experience long-term drug-resistant chronic pelvic pain, as well as other symptoms associated with pelvic mass. In such cases, it is of great im...

    Authors: Krzysztof Gałczyński, Maciej Jóźwik, Dorota Lewkowicz, Anna Semczuk-Sikora and Andrzej Semczuk

    Citation: Journal of Ovarian Research 2019 12:104

    Content type: Review

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  27. Epithelial ovarian cancer (EOC) is usually diagnosed late at an advanced stage. Though EOC initially responds to treatment, the recurrence rate is pretty high. The efficacy of different targeted therapies redu...

    Authors: Sudeep Gupta, Shona Nag, Shyam Aggarwal, Amit Rauthan and Narayanankutty Warrier

    Citation: Journal of Ovarian Research 2019 12:103

    Content type: Review

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  28. Breast cancer is the most common cancer in young women. Fortunately current survival rates of BC are significant which makes future fertility very important for quality of life of BC survivors. Chemotherapy ca...

    Authors: Cristina Silva, Ana Cristina Ribeiro Rama, Sérgio Reis Soares, Mariana Moura-Ramos and Teresa Almeida-Santos

    Citation: Journal of Ovarian Research 2019 12:102

    Content type: Research

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  29. Ovarian carcinoma is a lethal gynecological malignancy. Women with ovarian cancer (OC) are highly recurrent and typically diagnosed at late stage. Ten-eleven translocation protein 3 (TET3) belongs to the famil...

    Authors: Tiefeng Cao, Wenwei Pan, Xiaoli Sun and Huimin Shen

    Citation: Journal of Ovarian Research 2019 12:101

    Content type: Review

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  31. Ovarian cancer is the most common gynecological malignancy that causes cancer-related deaths in women today; this being the case, developing an understanding of ovarian cancer has become one of the major drivi...

    Authors: Yingyu Dou, Xiaoyan Jiang, Hui Xie, Junyu He and Songshu Xiao

    Citation: Journal of Ovarian Research 2019 12:99

    Content type: Review

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  32. Endometriosis patients undergoing in vitro fertilization-embryo transfer (IVF-ET) treatment suffer from lower success rates. The success of IVF-ET is related to the receptivity of the uterus and the quality of...

    Authors: Yu Liang, Xiaokui Yang, Yonglian Lan, Lingling Lei, Ying Li and Shuyu Wang

    Citation: Journal of Ovarian Research 2019 12:98

    Content type: Research

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  33. Polycystic ovary syndrome (PCOS) is a common reproductive endocrine disorder characterized by obesity, hyperandrogenism, and insulin resistance. Intercellular adhesion molecule-1 (ICAM-1) is a proinflammatory ...

    Authors: Nearmeen M. Rashad, Amal S. El-Shal, Hala G. Abomandour, Amr Mostafa Kamel Aboelfath, Mohamed el sayed Rafeek, Mohammad Samir Badr, Ayman E. Ali, Mohammed S. Yousef, Maha Abdelhamid Fathy and Mustafa taha Abdelfattah Sharaf el din

    Citation: Journal of Ovarian Research 2019 12:97

    Content type: Research

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  34. Development of a hyper-gonadotropic hypoestrogenism condition in women < 40 years, defined as premature ovarian insufficiency (POI), is the most common long-term complication in female survivors of galactosemi...

    Authors: Marzieh Rostami Dovom, Mahsa Noroozzadeh, Nariman Mosaffa, Azita Zadeh–Vakili, Abbas Piryaei and Fahimeh Ramezani Tehrani

    Citation: Journal of Ovarian Research 2019 12:96

    Content type: Review

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  35. Large cell neuroendocrine carcinoma is a very rare ovarian neoplasm that has a poor clinical outcome even in the early stage, and there is as yet no established treatment. Diagnostic laparoscopy has been used ...

    Authors: Hideaki Tsuyoshi, Kenji Yashiro, Shizuka Yamada, Makoto Yamamoto, Toshimichi Onuma, Tetsuji Kurokawa and Yoshio Yoshida

    Citation: Journal of Ovarian Research 2019 12:95

    Content type: Case report

    Published on:

  36. The polycystic ovary syndrome (PCOS) is a reproductive endocrine disorder, clinically characterized by oligo-ovulation/chronic anovulation, menstrual irregularities, hyperandrogenism (such as hirsutism, acne),...

    Authors: Zeng-Hong Wu, Yun Tang, Xun Niu, Fei-Fei Pu, Xi-Yue Xiao and Wen Kong

    Citation: Journal of Ovarian Research 2019 12:94

    Content type: Review

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  37. The ST6Gal-I glycosyltransferase, which adds α2–6-linked sialic acids to N-glycosylated proteins is upregulated in a wide range of malignancies including ovarian cancer. Prior studies have shown that ST6Gal-I-med...

    Authors: Kaitlyn A. Dorsett, Robert B. Jones, Katherine E. Ankenbauer, Anita B. Hjelmeland and Susan L. Bellis

    Citation: Journal of Ovarian Research 2019 12:93

    Content type: Research

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  38. AB209371 gene has been characterized as an oncogenic lncRNA in liver cancer. However, its involvement in ovarian carcinoma (OC) is unknown. In the present study, we analyzed the roles of AB209371 in OC. We fou...

    Authors: Zi-Hui Zheng, Dong-Mei Wu, Shao-Hua Fan, Xin Wen, Xin-Rui Han, Shan Wang, Yong-Jian Wang, Zi-Feng Zhang, Qun Shan, Meng-Qiu Li, Bin Hu, Yuan-Lin Zheng and Jun Lu

    Citation: Journal of Ovarian Research 2019 12:92

    Content type: Research

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  39. A retrospective case-control study was performed to evaluate whether PCOS-specific serum markers would change in women with polycystic ovary syndrome (PCOS) during the course of two consecutive cycles of clomi...

    Authors: Marlene Hager, Steffen Hörath, Peter Frigo, Marianne Koch, Rodrig Marculescu and Johannes Ott

    Citation: Journal of Ovarian Research 2019 12:91

    Content type: Research

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  40. Phospholipase C (PLC) can participate in cell proliferation, differentiation and aging. However, whether it has a function in apoptosis in porcine primary granulosa cells is largely uncertain. The objective of...

    Authors: Huali Chen, Youfu Yang, Youlin Wang, Yuan Li, Yamei He, Jiaxin Duan, Dejun Xu, Yifei Pei, Jianyong Cheng, Li Yang, Rongmao Hua, Xiaoya Li, Jie Wang, Xiaohan Jiang, Huanshan He, Lin Wu…

    Citation: Journal of Ovarian Research 2019 12:90

    Content type: Research

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  41. Gonadoblastoma (GB) is a rare mixed germ cell-sex cord-stromal tumour, first described in humans, commonly found in dysgenetic gonads of intersex patients that have a Y chromosome. However, this entity in not ...

    Authors: Ana R. Flores, João Lobo, Francisco Nunes, Alexandra Rêma, Paula Lopes, Luís Carvalho, Carla Bartosch, Irina Amorim and Fátima Gärtner

    Citation: Journal of Ovarian Research 2019 12:89

    Content type: Case report

    Published on:

  42. Epithelial ovarian cancer (EOC) is the majority ovarian cancer (OC) type with a poor prognosis. This present study aimed to investigate potential prognostic factors including albumin-to-fibrinogen ratio (AFR) ...

    Authors: Wen Yu, Zhongxue Ye, Xi Fang, Xingzhi Jiang and Yafen Jiang

    Citation: Journal of Ovarian Research 2019 12:88

    Content type: Research

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  43. This study aimed to examine the performance of the four risk of malignancy index (RMI) in discriminating borderline ovarian tumors (BOTs) and benign ovarian masses in daily clinical practice.

    Authors: Shuang Zhang, Shan Yu, Wenying Hou, Xiaoying Li, Chunping Ning, Yingnan Wu, Feng Zhang, Yu Fei Jiao, Leo Tsz On Lee and Litao Sun

    Citation: Journal of Ovarian Research 2019 12:87

    Content type: Research

    Published on:

  45. To compare the chemoresistance and survival in patients with stage IIIC or IV epithelial ovarian cancer who were treated with neoadjuvant chemotherapy (NACT) followed by interval debulking surgery (IDS) or pri...

    Authors: Yan Gao, Yuan Li, Chunyu Zhang, Jinsong Han, Huamao Liang, Kun Zhang and Hongyan Guo

    Citation: Journal of Ovarian Research 2019 12:85

    Content type: Research

    Published on:

  46. Circular RNAs (circRNAs) are a class of long non-coding RNAs (lncRNAs) which have a circular and closed loop structure. They are ubiquitous, stable, conserved and diverse RNA molecules with a range of activiti...

    Authors: Zahra Shabaninejad, Asma Vafadar, Ahmad Movahedpour, Younes Ghasemi, Afshin Namdar, Hadis Fathizadeh, Mohammad Hossein Pourhanifeh, Amir Savardashtaki and Hamed Mirzaei

    Citation: Journal of Ovarian Research 2019 12:84

    Content type: Review

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  47. The incidence of Cesarean has increased in recent years. The purpose of this study is to evaluate the effect of cesarean section on ovarian reserve.

    Authors: Ashraf Moini, Reihaneh Pirjani, Maryam Rabiei, Maryam Nurzadeh, Mahdi Sepidarkish, Reihaneh Hosseini and Ladan Hosseini

    Citation: Journal of Ovarian Research 2019 12:83

    Content type: Research

    Published on:

  48. Polycystic ovary syndrome (PCOS) is an endocrine disease that is common in women in their reproductive period. Patients with this disease suffer from anovulation and hyperandrogenism. Ovulation induction with ...

    Authors: Sachiko Nagao, Tsuyoshi Baba, Yuya Fujibe, Sayaka Adachi, Keiko Ikeda, Miyuki Morishita, Yoshika Kuno, Hiroyuki Honnma, Toshiaki Endo, Tamotsu Kiya and Tsuyoshi Saito

    Citation: Journal of Ovarian Research 2019 12:82

    Content type: Research

    Published on:

  49. Uterine corpus endometrial carcinoma (UCEC) is one of the most common cancer in female worldwide. PIK3CA has been proven to be a strong prognostic biomarker in UCEC. Nevertheless, current studies have not inve...

    Authors: Yinglian Pan, Li Ping Jia, Yuzhu Liu, Yixu Han and Qingchun Deng

    Citation: Journal of Ovarian Research 2019 12:81

    Content type: Research

    Published on:

  50. Multiple targeted gene sequencing is seldom performed in both germline and somatic testing for ovarian cancer. This study is to evaluate the specific genetic alterations, including both somatic and germline mu...

    Authors: Wenhui Li, Di Shao, Lei Li, Ming Wu, Shuiqing Ma, Xianjie Tan, Sen Zhong, Fengming Guo, Zhe Wang and Mingzhi Ye

    Citation: Journal of Ovarian Research 2019 12:80

    Content type: Research

    Published on:

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