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  1. The number of cases of novel coronavirus disease 2019 (COVID-19) in Japan have risen since the first case was reported on January 24, 2020, and 6225 infections have been reported as of June 30, 2020. On April ...

    Authors: Yuya Nogami, Yusuke Kobayashi, Kosuke Tsuji, Megumi Yokota, Hiroshi Nishio, Masaru Nakamura, Wataru Yamagami, Tohru Morisada, Eiichiro Tominaga, Kouji Banno and Daisuke Aoki

    Citation: Journal of Ovarian Research 2020 13:105

    Content type: Case report

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  2. Circular RNAs (circRNAs) are a newly discovered class of endogenous non-coding RNAs that play an important role in growth and development by regulating gene expression and participating in a variety of biologi...

    Authors: Su Xie, Mengxun Li, Yansen Chen, Yi Liu, Lipeng Ma, Xiaomei Sun, Yishan Sun, Ruonan Gao and Tao Huang

    Citation: Journal of Ovarian Research 2020 13:104

    Content type: Research

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  4. In clinical practice alterations in CA-125 concentration within normal range in patients with ovarian cancer after first-line treatment are common. Even minor increase in CA-125 concentration is associated wit...

    Authors: Szymon Piatek, Grzegorz Panek, Zbigniew Lewandowski, Mariusz Bidzinski, Dominika Piatek, Przemyslaw Kosinski and Miroslaw Wielgos

    Citation: Journal of Ovarian Research 2020 13:102

    Content type: Research

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  5. Detailed epidemiologic descriptions of large populations of advanced stage ovarian cancer patients have been lacking to date. This study aimed to describe the patient characteristics, treatment patterns, survi...

    Authors: Daniel C. Beachler, Francois-Xavier Lamy, Leo Russo, Devon H. Taylor, Jade Dinh, Ruihua Yin, Aziza Jamal-Allial, Samuel Dychter, Stephan Lanes and Patrice Verpillat

    Citation: Journal of Ovarian Research 2020 13:101

    Content type: Research

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  6. Ovarian cancer typically is diagnosed late because insensitivity and lack of specificity of current biomarkers prior to its clinical detection. Ribosomal protein S6 (RPS6) is a ribosomal protein involved in th...

    Authors: Xueqing Yang, Luxi Xu, Yu-e Yang, Chang Xiong, Jinjin Yu, Yuan Wang and Yaying Lin

    Citation: Journal of Ovarian Research 2020 13:100

    Content type: Research

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  7. Ovarian cancer is the second most common gynecologic cancer with high mortality rate and generally diagnosed in advanced stages. The 5-year disease-free survival is below 40%. MicroRNAs, subset of the non-codi...

    Authors: Seref Bugra Tuncer, Ozge Sukruoglu Erdogan, Seda Kilic Erciyas, Mukaddes Avsar Saral, Betul Celik, Demet Akdeniz Odemis, Gozde Kuru Turkcan and Hulya Yazici

    Citation: Journal of Ovarian Research 2020 13:99

    Content type: Research

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  8. Intercellular exchange between the oocyte and its surrounding cells within the follicular environment is critical for oocyte maturation and subsequent development. In vertebrates this exchange is facilitated t...

    Authors: Zachary Timothy Dye, Lauren Virginia Rutledge, Silvia Penuela and Paul William Dyce

    Citation: Journal of Ovarian Research 2020 13:98

    Content type: Research

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  10. In the context of a continuously increased delay of motherhood and of an increase of the incidence of premature ovarian failure, it is of the greatest interest to dispose of a predictive marker of the duration...

    Authors: Anne-Julie Fattet, Simon Toupance, Simon N. Thornton, Nicolas Monnin, Jean-Louis Guéant, Athanase Benetos and Isabelle Koscinski

    Citation: Journal of Ovarian Research 2020 13:96

    Content type: Review

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  11. Ovarian cancer is the leading cause of cancer-related death among women. Complete cytoreductive surgery followed by platinum-taxene chemotherapy has been the gold standard for a long time. Various compounds ha...

    Authors: Kuo-Chang Wen, Pi-Lin Sung, Alexander T. H. Wu, Ping-Chieh Chou, Jun-Hung Lin, Chi-Ying F. Huang, Sai-Ching J. Yeung and Mong-Hong Lee

    Citation: Journal of Ovarian Research 2020 13:95

    Content type: Research

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  12. To determine if a modified ovarian sensitivity index (MOSI), based on initial follicular measurements and the initial follicle-stimulating hormone (FSH) dose, can predict the production of high-quality embryos...

    Authors: David Camargo-Mattos, Uziel García, Felipe Camargo-Diaz, Ginna Ortiz, Ivan Madrazo and Esther Lopez-Bayghen

    Citation: Journal of Ovarian Research 2020 13:94

    Content type: Research

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  13. Cumulus cells (CC) encapsulate growing oocytes and support their growth and development. Transcriptomic signatures of CC have the potential to serve as valuable non-invasive biomarkers for oocyte competency an...

    Authors: Brandon A. Wyse, Noga Fuchs Weizman, Seth Kadish, Hanna Balakier, Mugundhine Sangaralingam and Clifford L. Librach

    Citation: Journal of Ovarian Research 2020 13:93

    Content type: Research

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  14. MicroRNAs (miRNAs) play crucial functions in the progression of ovarian cancer. MicroRNA-27b-5p (miR-27b-5p) has been identified as a cancer-associated miRNA. Nevertheless, the expression profile of miR-27b-5p...

    Authors: Chun Hua Liu, Xue Ning Jing, Xiao Lan Liu, Shan Yong Qin, Min Wei Liu and Chun Hong Hou

    Citation: Journal of Ovarian Research 2020 13:92

    Content type: Research

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  15. In order to investigate whether adjuvant chemotherapy is essential for patients with early-stage serous and endometrioid epithelial ovarian cancer, the present study collected data from the US Surveillance, Ep...

    Authors: Shuqing Li and Zhiling Zhu

    Citation: Journal of Ovarian Research 2020 13:91

    Content type: Research

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  16. MiRNAs play important roles in the development of ovarian cancer, activation of primitive follicles, follicular development, oocyte maturation and ovulation. In the present study, we investigated the specific ...

    Authors: Ji Lin, Huijuan Huang, Liheng Lin, Weiwei Li and Jianfen Huang

    Citation: Journal of Ovarian Research 2020 13:90

    Content type: Research

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  17. This study attempts to evaluate whether preoperative systemic inflammatory response (SIR) markers or other hematological variables, such as albumin, D-dimer, and carbohydrate antigen 125, play roles in predict...

    Authors: Wei Chen, Siyuan Zhong, Boer Shan, Shuling Zhou, Xiaohua Wu, Huijuan Yang and Shuang Ye

    Citation: Journal of Ovarian Research 2020 13:89

    Content type: Research

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  18. This study aims to determine the impact of assisted hatching (AH) on pregnancy outcomes in vitrified-warmed blastocyst transfers, and evaluate if embryo expansion or morphology influences outcomes.

    Authors: Charis Ng, Marta Wais, Taryn Nichols, Sarah Garrow, Julius Hreinsson, Zhong-Cheng Luo and Crystal Chan

    Citation: Journal of Ovarian Research 2020 13:88

    Content type: Research

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  19. Whether menstrual variability in women with regular and ovulatory cycle could affect embryo implantation remains controversial, with conflicting evidences presented in the literature. Thus, in this study, we e...

    Authors: Ying Ying, Fuman Qiu, Qing Huang, Sichen Li, Haiying Liu and Jianqiao Liu

    Citation: Journal of Ovarian Research 2020 13:87

    Content type: Research

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  20. The current study evaluated the metalloproteinases MMP-2 and MMP-9 expression in epithelial cells and the surrounding stroma in ovarian tumors and the association of MMPs with the histological subtypes, the cl...

    Authors: Flavia Morales-Vásquez, Rocío Castillo-Sánchez, María J. Gómora, Miguel Ángel Almaraz, Enrique Pedernera, Delia Pérez-Montiel, Elizabeth Rendón, Horacio Noé López-Basave, Edgar Román-Basaure, Sergio Cuevas-Covarrubias, Juan Maldonado-Cubas, Antonio Villa and Carmen Mendez

    Citation: Journal of Ovarian Research 2020 13:86

    Content type: Research

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  21. Wnt-inducible signaling pathway protein 2 (WISP2) is a wnt1-induced signaling pathway protein 2. Although studies indicate that WISP2 may promote the development of various tumors, its role in ovarian cancer r...

    Authors: Zi-Qing Shi, Zi-Yan Chen, Yao Han, Heng-Yan Zhu, Meng-Dan Lyu, Han Zhang, Yi Zhang, Liu-Qing Yang and Wei-Wei Pan

    Citation: Journal of Ovarian Research 2020 13:85

    Content type: Research

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  23. Ovarian cancer (OvCa) is one of the most lethal tumors of gynecologic malignancies, due to lack of early detection, and a high rate of metastasis. The standard treatment for OvCa is surgery and cytotoxic chemo...

    Authors: Caroline E. Ukwade, Osaretin A. T. Ebuehi, Rahmat A. Adisa, Santosh K. Singh and Rajesh Singh

    Citation: Journal of Ovarian Research 2020 13:83

    Content type: Research

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  24. Serous ovarian carcinomas (SCA) are the most common and most aggressive ovarian carcinoma subtype which etiology remains unclear. To investigate the prospective role of mRNAs in the tumorigenesis and progressi...

    Authors: Hongjun Fei, Songchang Chen and Chenming Xu

    Citation: Journal of Ovarian Research 2020 13:82

    Content type: Research

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  25. circular RNAs (circRNAs) have been reported to be essential regulators of multiple malignant cancers. However, the functions of circRNAs in ovarian cancer need to be further explored. The aim of our study is t...

    Authors: Qin Xu, Bo Deng, Manlin Li, Yang Chen and Li Zhuan

    Citation: Journal of Ovarian Research 2020 13:81

    Content type: Research

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  26. Problems with fallopian tubes are one of the main reasons for women to undergo in vitro fertilization-embryo transfer (IVF-ET). A large proportion of women with ectopic pregnancy, fallopian tube obstruction an...

    Authors: Tong Chen, Feiyan Zhao, Qin Wang, Chang Liu, Yonglian Lan, Shuyu Wang, Zhimin Xin and Xiaokui Yang

    Citation: Journal of Ovarian Research 2020 13:80

    Content type: Research

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  28. We sought to determine the impact of pretreatment plasma platelet levels, dimerized plasmin fragment (D-dimer) and fibrinogen in recurrent epithelial ovarian cancer (EOC) and the impact of platelet levels on S...

    Authors: Qinghong Hu, Abha Hada and Liping Han

    Citation: Journal of Ovarian Research 2020 13:78

    Content type: Research

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  31. Ovarian squamous cell carcinoma (SCC) is a rare cancer with possible poor survival, however no direct evidence supports this viewpoint and the independent prognostic factors are controversial. Patients with ov...

    Authors: Cheng Zhang and Tai Ma

    Citation: Journal of Ovarian Research 2020 13:75

    Content type: Research

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  36. The prognostic value and optimal resection outcome related factors of the secondary cytoreduction surgery (SCR) in Platinum-sensitive recurrent ovarian cancer (PSOC) patients were still in doubt. The present r...

    Authors: Hongyuan Gu, Rui Zhou, Jing Ni, Xia Xu, Xianzhong Cheng, Yan Li and Xiaoxiang Chen

    Citation: Journal of Ovarian Research 2020 13:70

    Content type: Research

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  37. The aim of this study was to determine whether the treatment with doxycycline before and after oocyte retrieval is as effective as salpingectomy in minimizing the detrimental effect of hydrosalpinx on the outc...

    Authors: Usama M. Fouda, Hesham S. Elshaer, Mohamed A. Youssef and Fatma F. Darweesh

    Citation: Journal of Ovarian Research 2020 13:69

    Content type: Research

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  38. Cervical cancer is considered as an important malignancy among women worldwide. Currently-used treatments of cervical cancer are reported to be cytotoxic for patients. Moreover, these therapies have shown some...

    Authors: Moghaddaseh Jahanshahi, Parisa Maleki Dana, Bita Badehnoosh, Zatollah Asemi, Jamal Hallajzadeh, Mohammad Ali Mansournia, Bahman Yousefi, Bahram Moazzami and Shahla Chaichian

    Citation: Journal of Ovarian Research 2020 13:68

    Content type: Review

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  39. Ovarian cancer is the most fatal gynecologic malignancy worldwide due to its vagueness, delay in diagnosis, recurrence, and drug resistance. Therefore, a new type of ovarian cancer treatment prediction biomark...

    Authors: Ze Li, Yongwang Hou, Meng Zhao, Tianning Li, Yahui Liu, Jiao Chang and Li Ren

    Citation: Journal of Ovarian Research 2020 13:67

    Content type: Research

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  40. Co-administration of letrozole during the first 5 days of ovarian stimulation was suggested to improve IVF outcomes in poor responders. We aimed to determine whether poor/sub-optimal responders might benefit f...

    Authors: Moran Shapira, Raoul Orvieto, Oshrit Lebovitz, Ravit Nahum, Adva Aizer, Aliza Segev-Zahav and Jigal Haas

    Citation: Journal of Ovarian Research 2020 13:66

    Content type: Research

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  41. High-grade serous carcinoma (HGSC) of the ovary is the most common subtype of epithelial ovarian cancer (EOC) and has an overall poor prognosis. There is increasing awareness of the importance of immune cell p...

    Authors: Kyung Un Choi, Ahrong Kim, Jee Yeon Kim, Ki Hyung Kim, Chungsu Hwang, So Jung Lee, Won Young Park, Sejin Jung, Hye Jeong Choi and Kyungbin Kim

    Citation: Journal of Ovarian Research 2020 13:65

    Content type: Research

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  42. Increasing researches have demonstrated the critical functions of circular RNAs (circRNAs) in the progression of malignant tumors, including ovarian cancer. In this study, we aim to investigate abnormally expr...

    Authors: Nan Zhang, Yue Jin, Qiubo Hu, Shanshan Cheng, Chao Wang, Zhiyou Yang and Yu Wang

    Citation: Journal of Ovarian Research 2020 13:64

    Content type: Research

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  43. Granulosa cells (GCs) are somatic cells surrounding oocytes within follicles and are essential for folliculogenesis. Pathological changes in GCs are found in several ovarian disorders. Recent reports have indi...

    Authors: Jiajie Tu, Yu Chen, Zhe Li, Huan Yang, He Chen and Zhiying Yu

    Citation: Journal of Ovarian Research 2020 13:63

    Content type: Review

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  44. Malignant transformation such as ovarian squamous cell carcinoma (SCC) in ovarian mature cystic teratoma (OMCT) is a rare tumor. The gene mutation of ovarian SCC remains unclear. We herein report a recurrent c...

    Authors: Xuhui Dong, Lei Yuan and Liangqing Yao

    Citation: Journal of Ovarian Research 2020 13:62

    Content type: Case report

    Published on:

  46. LncRNA TONSL-AS1 has been characterized as a critical player in gastric cancer. By analyze the TCGA dataset, we observed the upregulation of TONSL-AS1 in ovarian epithelial carcinoma (EOC). We therefore invest...

    Authors: Yan Liu, Ling Li, Xiangyang Wang, Ping Wang and Zhongxian Wang

    Citation: Journal of Ovarian Research 2020 13:60

    Content type: Research

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  47. Biomarkers are needed to guide treatment decisions in recurrent ovarian cancer, as a high proportion of patients do not benefit from treatments. Data on immune subsets in patients receiving chemotherapy are sc...

    Authors: Jon Røikjær Henriksen, Line Nederby, Frede Donskov, Marianne Waldstrøm, Parvin Adimi, Anders Jakobsen and Karina Dahl Steffensen

    Citation: Journal of Ovarian Research 2020 13:59

    Content type: Research

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  48. A hallmark of epithelial ovarian cancer (EOC) metastasis is the process of spheroid formation, whereby tumour cells aggregate into 3D structures while in suspension in the peritoneal cavity. EOC spheroids are ...

    Authors: Jeremi Laski, Bipradeb Singha, Xu Wang, Yudith Ramos Valdés, Olga Collins and Trevor G. Shepherd

    Citation: Journal of Ovarian Research 2020 13:58

    Content type: Research

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  50. The therapeutic value of systematic lymphadenectomy during debulking surgery for ovarian cancer remains controversial. We conduct this meta-analysis to evaluate the significance of systematic lymphadenectomy i...

    Authors: Qingqing Lin, Wenchao Liu, Song Xu, Juan Li and Jinyi Tong

    Citation: Journal of Ovarian Research 2020 13:56

    Content type: Research

    Published on:

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