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Table 1 Clinical, biochemical and hormonal features of participants

From: The gut microbial composition in polycystic ovary syndrome with insulin resistance: findings from a normal‐weight population

   PCOS
Parametes HC(n = 12) NIR(n = 10) IR(n = 14)
Age(years) 28.25 ± 1.22 26.4 ± 3.41 26.71 ± 2.43
Menstrual cycle(days) 29.67 ± 2.02AB 82.7 ± 26.61B 75.43 ± 27.91 A
BMI(Kg/m2) 21.28 ± 1.34 21.32 ± 1.22 21.91 ± 1.4
Waist 67.42 ± 4.4AB 71.8 ± 3.29BC 77.79 ± 5.73AC
Hip 88 ± 5.31 87.8 ± 3.33 91.54 ± 4.43
Waist to hip ratio 0.77 ± 0.03AB 0.82 ± 0.03BC 0.85 ± 0.04AC
FPG (mmol/L) 5 ± 0.27 A 5.09 ± 0.47 5.42 ± 0.59 A
FINs(uU/mL) 6.91 ± 1.82 A 6.95 ± 2.52 C 14.81 ± 3.88AC
HOMA-IR 1.54 ± 0.45 A 1.61 ± 0.64 C 3.57 ± 1.07AC
HbA1-C 5.04 ± 0AB 5.37 ± 0.21B 5.26 ± 0.28 A
FSH (IU/L) 6.8 ± 2.18 5.92 ± 2.16 6.43 ± 1.42
LH(IU/L) 6.25 ± 2.88AB 15.55 ± 8.03B 15.37 ± 7.31 A
LH/FSH 0.96 ± 0.4AB 2.53 ± 0.89B 2.42 ± 1.2 A
T (nmol/L) 0.75 ± 0.21AB 1.93 ± 0.57B 1.81 ± 0.82 A
P(nmol/l) 0.54 ± 0.16B 0.93 ± 0.52B 0.74 ± 0.43
E2(pmol/L) 183.51 ± 100.9B 281.47 ± 164.67B 194.25 ± 55.9
AMH 4.99 ± 3.74 A 7.99 ± 2.79 9.28 ± 5.12 A
TBA (umol/l) 4.7 ± 2.22 5.51 ± 4.77 5.26 ± 2.4
ALT (U/L) 13.18 ± 2.7 21.02 ± 15.13 20.81 ± 11.77
AST(U/L) 18.22 ± 5.91 22.03 ± 6.72 21.64 ± 6.4
Lithic (umol/L) 243.43 ± 37.04B 320.21 ± 56.66B 283.65 ± 105.62
TG( mmol/L) 0.88 ± 0.25 A 1.14 ± 0.84 1.29 ± 0.41 A
TC( mmol/L) 4.29 ± 1.11 4.39 ± 0.68 4.77 ± 0.88
HDL(mmol/L) 1.47 ± 0.31 1.36 ± 0.26 1.33 ± 0.23
LDL(mmol/L) 2.67 ± 0.59 2.6 ± 0.53 2.9 ± 0.6
APO-a 93.13 ± 71.68 120.14 ± 126.97 194.49 ± 220.43
ApoA/ApoB 2.47 ± 0.48 2.31 ± 0.56 2.22 ± 0.62
FFA(mmol/L) 0.47 ± 0.11 A 0.48 ± 0.31 0.66 ± 0.24 A
hsCRP(mg/L) 0.69 ± 0.56 A 0.8 ± 0.75 C 1.63 ± 1.27AC
IL-6(pg/ml) 1.13 ± 0.46AB 2.12 ± 0.26B 2.56 ± 1.28 A
TNF 3.76 ± 1.43AB 4.86 ± 1.07B 4.54 ± 0.51 A
  1. A: P < 0.05 for HC vs. IR-PCOS group
  2. B: P < 0.05 for HC vs. NIR-PCOS group
  3. C: P < 0.05 for IR vs. NIR-PCOS group
  4. Abbreviation: PCOS polycystic ovary syndrome; PCOS-IR PCOS with insulin resistance; PCOS-NIR PCOS withoutinsulin resistance; BMI body mass index; WHR the ratio of waist to hip; FSH follicular stimulating hormone; LHluteinizing hormone; TNF-a tumor necrosis factor-a; FPG fasting plasma glucose; FINS fasting plasma insulin;HOMAIR homeostasis model assessment of insulin resistance; PPG 3h postprandial plasma glucose; TC totalcholesterol; HDL-C high density lipoprotein-cholesterol; LDL-C low density lipoprotein-cholesterol; ALT alanine aminotransferase; AST aspartate aminotransferase
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