Fig. 5

Notch signaling pathway was involved in the regulation of miR-1271-5p/TIAM1 in OC development. a-b The levels of Cyclin D1, HES1, NOTCH and NUMB were tested by western blot in transfected OVCAR-3 and SK-OV-3 cells. The quantitative of protein intensity were also showed in histograms, ^**P < 0.01 versus NC group, ^##P < 0.01 versus inhibitor or mimic group, ^&&P < 0.01 versus si-TIAM1 or TIAM1 group