Table 1 Clinical and hormonal characteristics of the patients with POI
| Case ID | Age (Years) |
Menopause age (Years) | BMI (kg/m2) |
Primary or secondary amenorrhea | FSH (IU/L) | LH (IU/L) | E2 (pg/mL) | Karyotype |
Ovary size (right/ left, mm) | Follicle |
|---|---|---|---|---|---|---|---|---|---|---|
| POI-1 | 35 | 33 | 25.20 | secondary | 35.92 | 16.61 | 24 | 46,XX | 21*16/22*18 | Rare |
| POI-3 | 29 | 27 | 28.25 | secondary | 161.18 | 56.92 | 21 | 46,XX | 18*11/16*11 | Absent |
| POI-6 | 30 | 28 | 24.14 | secondary | 73.77 | 27.56 | 79 | 46,XX | 19*11/18*12 | Absent |
| POI-7 | 23 | 13 | 23.80 | primary | 127.54 | 39.5 | 34 | 46,XX | 15*10/13*9 | Absent |
| POI-8 | 25 | 15 | 25.71 | primary | 92.93 | 43.38 | 13 | 46,XX | 10*6/11*5 | Absent |
| POI-9 | 24 | 18 | 25.46 | secondary | 102.8 | 38.39 | 20 | 46,XX | 18*9/21*8 | Absent |
| POI-11 | 32 | 31 | 22.31 | secondary | 48.65 | 40.24 | 18 | 46,XX | 19*12/17*15 | Rare |
| POI-12 | 28 | 27 | 25.65 | secondary | 86.57 | 35.77 | 22 | 46,XX | 16*11/15*9 | Rare |
| POI-14 | 30 | 28 | 22.83 | secondary | 110.38 | 51.60 | 16 | 46,XX | 17*14/16*10 | Absent |
| POI-17 | 25 | 24 | 22.86 | secondary | 55.24 | 36.83 | 15 | 46,XX | 20*14/21*17 | Rare |
| POI-18 | 27 | 26 | 27.55 | secondary | 60.45 | 50.46 | 18 | 46,XX | 18*10/17*8 | Rare |
| POI-21 | 22 | 14 | 23.07 | primary | 107.28 | 38.55 | 24 | 46,XX | 11*6/12*5 | Absent |
| POI-23 | 26 | 25 | 25.81 | secondary | 38.50 | 24.69 | 15 | 46,XX | 17*15/16*13 | Rare |
| POI-24 | 16 | 13 | 24.31 | primary | 49.66 | 35.52 | 33 | 46,XX | 10*5/11*4 | Absent |